Research Group of Cell Biology of Green Algae and Cilia
PI: Prof. HUANG Kaiyao, PhD
Members: Dr. Huan Long, Xuan Deng, Rongli Miao, Hui Zeng, Zedong Xu, Kun Wang, Jun Zhang, Huifang Sun
Address: 7 South Donghu Road, Wuhan, 430072, China
Established in 2011, the Research Group of Cell Biology of Green Algae and Cilia mainly focuses on algal cell biology, molecular ecology, and synthetic biology. They have published 27 research papers in Nature, Current Biology, Nature Communication, Plant Journal, Journal of Cell Science, and other peer reviewed academic journals; won IHB’s ‘Excellent Article Award’ twice.
This group has presided over and undertaken one major research program of the National Natural Science Foundation of China (NSF), four general and two youth projects of the NSFC, one national key research and development program of synthetic biology, two 863 programs and two major projects of technological innovation in Hubei Province, with a total funding of more than 16 million yuan. Up to now, ten graduate students and 21 doctoral and master degree students have been trained from this group.
Major research interests:
* Molecular mechanism of cilia/flagellum formation, movement and ciliary ectosome secretion.
* The mechanism of carbon metabolism and acclimation to low temperature and high radiation in snow algae.
* Establishment of functional genomics and synthetic biology research platform in Chlamydomonas reinhardtii.
* Sensing and transformation mechanism of heavy metals Hg, Cr and Cd in microalgae.
* Development of organic selenium products from microalgae.
1. Huang K., Tsao C., 2010, Importin-β2: a key to two gates? 2010, Protein&Cell 1(9):791-792. (Huang K is corresponding author)
2. Huang K., Diener D., Rosenbaum J., 2009, The ubiquitin conjugation system is involved in the disassembly of cilia/flagella. Journal of Cell Biology, 186:601-613.
3. Huang K., Diener D., Mitchell A., Pazour G., Witman G., Rosenbaum J., 2007, Function and dynamics of PKD2 in Chlamydomonas flagella. Journal of Cell Biology, 179:501-514.
4. Soon Im C., Eberhard S., Huang K., Beck C., Grossman A., 2006. Phototropin involvement in expression of genes encoding chlorophyll and carotenoid biosynthesis enzymes and LHC apoproteins in Chlamydomonas reinhardtii. Plant Journal 48(1):1-16.
5. Huang K., Kunkel T., Beck. C. F., 2004. Localization of blue-light receptor phototropin to the flagella of the green alga Chlamydomonas reinhardtii. Mol. Biol. Cell. 15(8):3605-3614.
6. Huang K., Beck C.F., 2003. Phototropin is the blue-light receptor that controls multiple steps in the sexual life cycle of the green alga Chlamydomonas reinhardtii. Proc. Natl. Acad. Sci. USA. 100:6269-6274.