2020 

(1) Sijia Fan , Jing Wang, Guangqing Yu , Fangjing Rong, Dawei Zhang, Chenxi Xu , Juan Du, Zhi Li , Gang Ouyang , Wuhan Xiao* . TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation. Journal of Biological Chemistry, 2020, doi: 10.1074/jbc.RA120.014538. (

2) Zhi Li , Sijia Fan , Jing Wang , Xiaoyun Chen, Qian Liao , Xing Liu , Gang Ouyang, Hong Cao , Wuhan Xiao* . Zebrafish F-box protein fbxo3 negatively regulates antiviral response through promoting K27-linked polyubiquitination of the transcription factors irf3 and irf7. Journal of Immunology, 2020, 205(7):1897-1908.

(3) Xiaolian Cai , Ziwen Zhou, Junji Zhu , Qian Liao , Dawei Zhang , Xing Liu , Jing Wang , Gang Ouyang , Wuhan Xiao* . Zebrafish hif-3α modulates erythropoiesis via regulation of gata-1 to facilitate hypoxia tolerance. Development, 2020, doi: 10.1242/dev.185116.

(4) Guangqing Yu , Xing Liu , Dawei Zhang, Jing Wang, Gang Ouyang , Zhu Chen, Wuhan Xiao *. Zebrafish nedd8 facilitates ovarian development and the maintenance of female secondary sexual characteristics via suppression of androgen receptor activity. Development, 2020, 147(18): dev.194886.

(5) Guangqing Yu , Xiong Li , Ziwen Zhou , Jinhua Tang , Jing Wang, Xing Liu, Sijia Fan , Gang Ouyang, Wuhan Xiao * . Zebrafish phd3 negatively regulates antiviral responses via suppression of irf7 transactivity independent of its prolyl hydroxylase activity. Journal of Immunology, 2020, 205(4):1135-1146.

(6) Gang Ouyang , Qian Liao , Dawei Zhang , Fangjing Rong , Xiaolian Cai, Sijia Fan , Junji Zhu , Jing Wang , Xing Liu , Xueqin Liu, Wuhan Xiao * . Zebrafish NF-κB/p65 is required for antiviral responses. Journal of Immunology, 2020, 204(11):3019-3029.

(7) Xing Liu , Chunchun Zhu, Huangyuan Zha , Jinhua Tang , Fangjing Rong, Xiaoyun Chen , Sijia Fan , Chenxi Xu , Juan Du, Junji Zhu, Jing Wang , Gang Ouyang , Guangqing Yu , Xiaolian Cai , Zhu Chen , Wuhan Xiao *. SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation. EMBO Journal, 2020, 39(11): e103285.

(8) Junji Zhu, Xing Liu, Xiaolian Cai, Gang Ouyang, Sijia Fan, Jing Wang, Wuhan Xiao*. Zebrafish prmt7 negatively regulates antiviral response by suppressing the retinoic acid-inducible gene 1-like receptor signaling. FASEB Journal, 2020, 34(1): 988-1000.

(9) Junji Zhu , Xing Liu , Xiaolian Cai , Gang Ouyang , Huangyuan Zha , Ziwen Zhou , Qian Liao , Jing Wang , Wuhan Xiao*. Zebrafish prmt3 negatively regulates antiviral responses. FASEB Journal, 2020, doi: 10.1096/ fj.201902569R

2019 

(10) Junji Zhu, Dawei Zhang, Xing Liu, Guangqing Yu, Xiaolian Cai, Chenxi Xu, Fangjing Rong, Gang Ouyang, Jing Wang, Wuhan Xiao*. Zebrafish prmt5 arginine methyltransferase is essential for germ cell development. Development, 2019, 146(20): dev179572.

(11) Guangqing Yu, Xing Liu, Jinghua Tang, Chenxi Xu, Gang Ouyang, Wuhan Xiao*. Neddylation Facilitates the Antiviral Response in Zebrafish. Frontiers in Immunology, 2019, 10: 1432.

2018 

(12) Xiaolian Cai, Dawei Zhang, Jing Wang, Xing Liu, Gang Ouyang, Wuhan Xiao*. Deletion of the fih gene encoding an inhibitor of hypoxia-inducible factors increases hypoxia tolerance in zebrafish. Journal of Biological Chemistry, 2018, 293(40): 15370-15380.

(13) Chenxi Xu, Xing Liu, Huangyuan Zha, Sijia Fan, Dawei Zhang, Wuhan Xiao*. A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1α protein. PLoS Pathogens, 2018, 18(8): e1007259.

2017 

(14) Jing Wang, Dawei Zhang, Juan Du, Chi Zhou, Zhi Li, Xing Liu, Gang Ouyang, Wuhan Xiao*. Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity. Nucleic Acids Research, 2017,45(22): 12700-12714.

(15) Dawei Zhang, Jing Wang, Chi Zhou, Wuhan Xiao*. Zebrafish akt2 is essential for survival, growth, bone development, and glucose homeostasis. Mechanisms of Development, 2017, 143:42-52.

2016 

(16) Xing Liu, Xiaolian Cai, Dawei Zhang, Chenxi Xu, Wuhan Xiao*. Zebrafish foxo3b negatively regulates anti-viral response through suppressing the transactivity of irf3 and irf7. Journal of Immunology, 2016, 197(12): 4736-4749.

(17) Xing Liu, Xiaolian Cai, Bo Hu, Zhichao Mei, Dawei Zhang, Gang Ouyang, Jing Wang, Wei Zhang, Wuhan Xiao*. Forkhead transcription factor (FOXO3a) modulates hypoxia signaling via up-regulation of the von Hippel-Lindau gene (VHL). Journal of Biological Chemistry, 2016, 291(49): 25692-25705.

(18) Yu Chen, Chi Zhou, Wei Ji, Zhichao Mei, Bo Hu, Wei Zhang, Dawei Zhang, Jing Wang, Xing Liu, Gang Ouyang, Jiangang Zhou, Wuhan Xiao*. ELL targets c-Myc for proteasomal degradation and suppresses tumor growth. Nature Communications, 2016, 7: 11057.

2015 

(19) Xing Liu, Zhu Chen, Gang Ouyang, Tieshan Song, Huageng Liang, Wei Liu, Wuhan Xiao*. ELL associated factor 2 (EAF2) inhibits transforming growth factor beta signaling through a direct interaction with Smad3. Journal of Biological Chemistry, 2015, 290(43): 25933-25945.

(20) Juan Du, Dawei Zhang. Wei Zhang, Gang Ouyang, Jing Wang, Xing Liu, Sun Li, Wei Liu, Wuhan Xiao*. pVHL negatively regulates antiviral signaling by targeting MAVS for proteasomal degradation. Journal of Immunology, 2015, 195(4): 1782-1790.

(21) Zhichao Mei, Dawei Zhang, Bo Hu, Jing Wang, Xian Shen, Wuhan Xiao*. FBXO32 targets c-Myc for proteasomal degradation and inhibits c-Myc activity. Journal of Biological Chemistry, 2015, 290(26): 16202-16214.

(22) Xing Liu, Zhu Chen, Chenxi Xu, Xiaoqian Leng, Hong Cao, Gang Ouyang, Wuhan Xiao*. Repression of hypoxia-inducible factor alpha signaling by Set7-mediated methylation. Nucleic Acids Research, 2015, 43(10): 5081-5098.

2014 

(23) Bo Hu, Wei Zhang, Xi Feng, Wei Ji, Xunwei Xie, Wuhan Xiao*. Zebrafish eaf1 suppresses foxo3b expression to modulate transcriptional activity of gata1 and spi1 in primitive hematopoiesis, Developmental Biology, 2014, 388: 81-93.

(24) Jing Wang, Wei Zhang, Wei Ji, Xing Liu, Gang Ouyang, Wuhan Xiao*. The Von Hippel-Lindau protein suppresses androgen receptor activity. Molecular Endocrinology, 2014, 28(2): 239-248.

(25) Zhu Chen, Xing Liu, Zhichao Mei, Zhou Wang*, Wuhan Xiao*. EAF2 suppresses HIF-1a transcriptional activity by disrupting its interaction with the co-activator CBP/p300. Molecular and Cellular Biology, 2014, 34(6): 1085-1099.

(26) Wei Zhang, Wei Ji, Xing Liu, Gang Ouyang, Wuhan Xiao*. ELL inhibits E2F1 transcriptional activity by enhancing E2F1 deacetylation via recruitment of Histone Deacetylase 1. Molecular and Cellular Biology, 2014, 34(4): 765-775.

(27) Wei Ji, Jing Wang, Wei Zhang, Xing Liu, Gang Ouyang, Wuhan Xiao*. pVHL acts as a downstream target of E2F1 to suppress E2F1 activity. Biochemical Journal, 2014, 457: 185-195.

2013 

(28) Jing-xia Liu, Dawei Zhang, Xunwei Xie, Gang Ouyang, Xing Liu, Yonghua Sun, Wuhan Xiao*. Eaf1 and Eaf2 negatively regulate canonical Wnt/beta-catenin signaling. Development, 2013, 140: 1067-1078.

2011 

(29) Xiaoyang Wan, Bo Hu, Jing-xia Liu, Xi Feng, Wuhan Xiao*. Zebrafish mll gene is essential for hematopoiesis. Journal of Biological Chemistry, 2011, 286: 33345-33357

(30) Xi Feng, Xing Liu, Wei Zhang, Wuhan Xiao*. p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death. EMBO Journal, 2011, 30: 3397-3415.

2009 

(31) Jiangang Zhou, Xi Feng, Bing Ban, Jing-xia Liu, Zhou Wang*, Wuhan Xiao*. The elongation factor ELL (Eleven-Nineteen Lysine-Rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation. Journal of Biological Chemistry, 2009, 284(28):19142-19152.

(32) Jing-xia Liu, Bo Hu, Yang Wang, Jianfang Gui, Wuhan Xiao*. Zebrafish eaf1 and eaf2/u19 mediate effective convergence and extension movements through the maintenance of wnt11 and wnt5 expression. Journal of Biological Chemistry, 2009, 284(24):16679-16692.