Research
| Name： | Zongbin CUI |
|---|---|
| Academic Title： | Professor |
| Education： | Ph.D. |
| Phone： | 86-27-68780090 |
| E-mail： | zbcui@ihb.ac.cn |
Resume：
Personal Data:
Dr. Cui obtained his B.S. in 1988 from Henan Normal University, M.S. in 1991 and Ph.D. in 1998 from the Institute of Hydrobiology (IHB), Chinese Academy of Sciences (CAS). As the third contributor, he received a first class Natural Science Award from CAS in 1996 and a third class State Natural Science Award in 1997. He won a second class Young Scientist Award from CAS and a Special Scholarship from the president of CAS in 1997.
Research Experience:
From June of 1991 through March of 1999, he worked in IHB on the generation of fast-growth transgenic fish. Between April of 1999 and March of 2002, he worked at the University of Minnesota in USA on fish developmental and molecular biology and obtained an International and United States Patent. Between March of 2002 and December of 2005, he worked in the medical center of University of Michigan on the mechanisms of normal repair and fibrosis after injury of tissues and organs. In January of 2006, he was supported by the "Hundred Talent Program" from CAS to set up a new research group in IHB. Currently, researches in his laboratory are mainly focused on the function, regulation and signaling pathways of fish genes relevant to embryonic development and cold resistance.
Selected Publications：
1. Qilin Gu, Xiaojie Yang, Li Lin, Shaoyang Li, Qing Li, Shan Zhong, Jinrong Peng, Zongbin Cui*, 2014. Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting. Hepatology, DOI: 10.1002/hep.27356
2. Guili Song, Zongbin Cui*, 2013. Novel strategies for gene trapping and insertional mutagenesis mediated by Sleeping Beauty transposon. Mobile Genetic Elements, 3(5): e26499.
3. Qilin Gu, Xiaojie Yang, Xiaozhen He, Qing Li, Zongbin Cui *, 2013. Generation and characterization of a transgenic zebrafish expressing the reverse tetracycline transactivator. Journal of Genetics and Genomics, 40: 523-531.
4. Yong Long, Guili Song, Junjun Yan, Xiaozhen He, Qing Li and Zongbin Cui*, 2013. Transcriptomic characterization of cold acclimation in larval zebrafish. BMC Genomics, 14:612.
5. Yong Long, Qing Li, Bolan Zhou, Guili Song, Tao Li, Zongbin Cui*, 2013. De Novo Assembly of Mud Loach (Misgurnus anguillicaudatus) Skin Transcriptome to Identify Putative Genes Involved in Immunity and Epidermal Mucus Secretion. PLoS ONE 8(2): e56998.
6. Xiaozhen He, Jie Li, Yong Long, Guili Song, Peiyong zhou, Qiuxiang Liu, Zuoyan Zhu, Zongbin Cui*, 2013. Gene transfer and mutagenesis mediated by Sleeping Beauty transposon in Nile tilapia (Oreochromis niloticus). Transgenic Res, 22: 913-924.
7. Guili Song, Qing Li, Yong Long, Qilin Gu, Perry B. Hackett and Zongbin Cui*, 2012. Effective gene trapping mediated by Sleeping Beauty transposon. PLoS ONE, 7(8): e44123.
8. Yong Long, Linchun Li, Qing Li, Xiaozhen He, Zongbin Cui*, 2012. Transcriptomic characterization of temperature stress responses in larval zebrafish. PLoS ONE, 7(5):e37209.
9. Guili Song, Qing Li, Yong Long, Perry B. Hackett and Zongbin Cui*,2012. Effective expression-independent gene trapping and mutagenesis mediated by Sleeping Beauty transposon. Journal of Genetics and Genomics, 39: 503-520.
10. Rui Wen, Jie Li, Xin Xu, Zongbin Cui*, Wei Xiao*, 2012. Zebrafish Mms2 promotes K63-linked polyubiquitination and is involved in p53-mediated DNA-damage response. DNA Repair. 11(2): 157-166.
11. Yuanyuan Li, Qing Li, Yong Long, Zongbin Cui*, 2011. Lzts2 regulates embryonic cell movements and dorsoventral patterning through interaction with and export of nuclear b-catenin in zebrafish. Journal of Biological Chemistry, 286(52): 45116-45130.
12. Hanqiao Shang, Qing Li, Guohui Feng, Zongbin Cui*, 2011. Identification and characterization of alternative promoters, transcripts and protein isoforms of zebrafish R2 gene. PLoS ONE 6(8): e24089.
13. Yong Long, Qing Li, Youhui Wang, Zongbin Cui*, 2011. MRP proteins as potential mediators of heavy metal resistance in zebrafish cells. Comp. Biochem.Physiol.C, 153: 310-317.
14. Yong Long, Qing Li, Zongbin Cui*, 2011. Molecular analysis and heavy metal detoxification of ABCC1/MRP1 in zebrafish. Molecular Biology Reports, 38:1703-1711.
15. Hanqiao Shang, Qing Li, Guohui Feng, Zongbin Cui*, 2011. Molecular analysis and functions of p53R2 in zebrafish. Gene, 475: 30-38.
16. Yong Long, Qing Li, Jie Li, Zongbin Cui*, 2011. Molecular analysis, developmental function and heavy metal-induced expression of ABCC5 in zebrafish. Comp.Biochem. Physiol. B, 158(1): 46-55.
17. Yong Long, Qing Li, Youhui Wang, Zongbin Cui*, 2011. Molecular characterization and functions of zebrafish ABCC2 in cellular efflux of heavy metals. Comp.Biochem.Physiol. C,153(4): 381-391.
18. Saijun Mo, Shengli Yang, Zongbin Cui*, 2011. New glimpses of caveolin-1 functions in embryonic development and human diseases. Frontiers in Biology, 6(5):367-376.
19. Saijun Mo, Lu Wang, Qing Li, Jie Li , Yuanyuan Li, Victor J. Thannickal, Zongbin Cui*, 2010. Caveolin-1 regulates dorsoventral patterning through direct interaction with β-catenin in zebrafish. Developmental Biology, 344: 210-223.
20. Jie Li, Rui Wen, Parkeer Andersen, Yuping Liang, Qing Li, Wei Xiao*, Zongbin Cui*, 2010. Zebrafish Ubc13 is required for Lys63-linked polyubiquitination and DNA damage tolerance. Molecular and Cellular Biochemistry, 343:173-182.
