Research
Title: | Metabolic Genes within Cyanophage Genomes: Implications for Diversity and Evolution |
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First author: | Gao, E-Bin; Huang, Youhua; Ning, Degang |
Journal: | GENES |
Years: | 2016 |
DOI: | 10.3390/genes7100080 |
Abstract: | Cyanophages, a group of viruses specifically infecting cyanobacteria, are genetically diverse and extensively abundant in water environments. As a result of selective pressure, cyanophages often acquire a range of metabolic genes from host genomes. The host-derived genes make a significant contribution to the ecological success of cyanophages. In this review, we summarize the host-derived metabolic genes, as well as their origin and roles in cyanophage evolution and important host metabolic pathways, such as the light-dependent reactions of photosynthesis, the pentose phosphate pathway, nutrient acquisition and nucleotide biosynthesis. We also discuss the suitability of the host-derived metabolic genes as potential diagnostic markers for the detection of genetic diversity of cyanophages in natural environments. |