Research

Publications
Title: Metabolic Genes within Cyanophage Genomes: Implications for Diversity and Evolution
First author: Gao, E-Bin; Huang, Youhua; Ning, Degang
Journal: GENES
Years: 2016
Volume / issue: 7 /
DOI: 10.3390/genes7100080
Abstract: Cyanophages, a group of viruses specifically infecting cyanobacteria, are genetically diverse and extensively abundant in water environments. As a result of selective pressure, cyanophages often acquire a range of metabolic genes from host genomes. The host-derived genes make a significant contribution to the ecological success of cyanophages. In this review, we summarize the host-derived metabolic genes, as well as their origin and roles in cyanophage evolution and important host metabolic pathways, such as the light-dependent reactions of photosynthesis, the pentose phosphate pathway, nutrient acquisition and nucleotide biosynthesis. We also discuss the suitability of the host-derived metabolic genes as potential diagnostic markers for the detection of genetic diversity of cyanophages in natural environments.