Education
Marine Biological Laboratory Woods Hole, MA
Fundamental Issues in Vision Research 2008
(Course director: Sandra K. Masur and David S. Papermaster)
University of Freiburg Freiburg, Germany
Ph. D., Molecular genetics 2003
Dissertation: Phototropin is the blue light receptor that controls multiple steps in the sexual life cycle of the green alga Chlamydomonas reinhardtii
Wuhan University Wuhan, China
Master, Genetics 1998
Transformation system of Cyanobacteria
Hubei University Wuhan, China
B.S., Biology 1992
Research Experience:
Institute of Hydrobiology.C.A.S Wuhan, China
Group Leader 2011-Present
Biogenesis and turnover of organelles cilia and oil droplets
Yale University New Haven, CT
Postdoctoral Fellow, Research Associate Scientist 2004-2011
Biogenesis and turnover of an organelle- the flagellum/cilium
─ Membrane vesicle trafficking from the cytoplasm, to the flagellum,and into the medium
─ Ubiquitin conjugate system in the flagella and its role in flagellar disassembly and signal transduction
High throughout screen of the putative drug for cilia related human diseases using Chlamydomonas flagellum as a model
University of Freiburg Freiburg, Germany
Graduate researcher; Advisor: Christopher F. Beck 1998-2004
Blue light receptor and blue light signaling in Chlamydomonas
─ Study the function of the blue light receptor in the sexual life cycle of Chlamydomonas
─ Examine the localization and function of the blue light receptor in the flagellum
1. Huang K., Tsao C., 2010, Importin-β2: a key to two gates? 2010, Protein&Cell 1(9):791-792. (Huang K is corresponding author)
2. Huang K., Diener D., Rosenbaum J., 2009, The ubiquitin conjugation system is involved in the disassembly of cilia/flagella. Journal of Cell Biology, 186:601-613.
3. Huang K., Diener D., Mitchell A., Pazour G., Witman G., Rosenbaum J., 2007, Function and dynamics of PKD2 in Chlamydomonas flagella. Journal of Cell Biology, 179:501-514.
4. Huang K., Kunkel T., Beck. C. F., 2004. Localization of blue-light receptor phototropin to the flagella of the green alga Chlamydomonas reinhardtii. Mol. Biol. Cell. 15(8):3605-3614.
5. Huang K., Beck C.F., 2003. Phototropin is the blue-light receptor that controls multiple steps in the sexual life cycle of the green alga Chlamydomonas reinhardtii. Proc. Natl. Acad. Sci. USA. 100:6269-6274.
6. Huang K., Merkle T., Beck C.F., 2002. Isolation and characterization of a Chlamydomonas gene that encodes a putative blue-light photoreceptor of the phototropin family. Physiol. Plant. 115:613-622.
